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O 2 •− is further converted to other ROS, such as H 2 O 2 , OH • , and hypochloric acid (HClO)

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In this pilot work, we have not conducted a formal evaluation as previously reported for NGRA approaches for systemic toxicity (Middleton et al., 2022), but rather we have investigated a proof-of-concept to establish the feasibility of defining a NAM toolbox to be included within an NGRA approach for lung toxicity